MADISON, Wis. (AP) — A Wisconsin beagle breeding farm that’s been the site of recent violent protests is closing, and its remaining dogs are being taken in by a Florida rescue group.

Big Dog Ranch Rescue announced Monday that it has reached an agreement for the permanent closure of Ridglan Farms and the transfer of its 475 remaining beagles starting this week.

“Not one dog will remain,” Lauree Simmons, the group’s founder, said in a news conference at a farm in Wisconsin. “No more breeding, no more testing, no more anything.”

The rescue group said some of the beagles will go to other rescue groups while others will be sent to its Florida and Alabama campuses where they will be spayed, neutered, and prepared for adoption.

The group bought roughly 1,500 of the farm’s more than 2,000 beagles in April for an undisclosed price.

About 200 dogs were transferred from the farm starting Monday morning, according to Simmons. Another 125 will be moved Tuesday. The transfer of the remaining beagles will happen in August, as they are still puppies.

Simmons called on protesters to refrain from further demonstrations as it says Ridglan Farms has committed to permanently closing its dog breeding, sales, research and testing operations.

She said her group and others are “working closely” with the Trump administration to stop funding studies that subject dogs to invasive and painful experimentation.

“Our focus now should be on supporting these dogs as they transition into their new lives,” Simmons said. “These dogs will get to experience safety and a normal life for the first time.”

Ridglan Farms, in a statement Monday, said all the dogs being transferred are “happy, healthy animals” with “extensive” state and federal inspection documentation.

“We hope these dogs will continue to flourish in their new homes,” the farm said, adding that the “years-long harassment campaign targeting the research facility’s owners, staff and neighbors comes to an end.”

The dog breeding and research business is located in Blue Mounds, a small town about 25 miles (about 40 kilometers) southwest of the capital, Madison.

Animal activists have been pushing for years to have dogs at the facility adopted, not sold to other research facilities.

Beagles are the most common breed of dog used for animal testing, primarily because of their smaller size and gentle temperament, according to Big Dog Ranch Rescue.

In April, police used tear gas and pepper spray to repel a large group of animal welfare activists that stormed the farm in an attempt to take beagles from the facility. Protesters also broke into the facility in March and took 30 dogs, leading to dozens of arrests.

Ridglan Farms agreed in October to give up its state breeding license as of July 1 as part of a deal to avoid prosecution on felony animal mistreatment charges.

The firm has denied mistreating animals, but a special prosecutor determined that Ridglan Farms was performing eye procedures that violated state veterinary standards.