Aramis Ramirez snapped a 2-all tie with a two-run homer to cap a four-run fifth inning as the Cubs doubled up the Astros, 4-2. Alfonso Soriano also homered and Starlin Castro had a sac-fly for Chicago, which took the opener of the three-game set at Wrigley Field. Carlos Zambrano pitched six innings of two-run ball for his seventh win. Five relievers followed, with Sean Marshall posting his third save. Bud Norris allowed all four runs in six and a third frames to suffer the loss. Michael Bourn went 3-for-5 with an RBI to highlight the Houston attack.